LBD
CDX1 Antibody (C-term) [AMM22151G]
- SKU:
- LBD-AMM22151G
- Availability:
- Usually ships in 5 working days
Description
CDX1 Antibody (C-term) [AMM22151G] | Gentaur UK, US & Europe Distribution
Product Category: Monoclonal Antibodies
Host: Mouse
Species Reactivity: H, M
Specificity: Purified His-tagged CDX1 protein was used to produced this monoclonal antibody.
Cellular Localisation: Nucleus.
Molecular Weight: 28138
Clone: Monoclonal
Gene Name: CDX1
Gene ID: 1044
Function: Plays a role in transcriptional regulation (PubMed:24623306) . Involved in activated KRAS-mediated transcriptional activation of PRKD1 in colorectal cancer (CRC) cells (PubMed:24623306) . Binds to the PRKD1 promoter in colorectal cancer (CRC) cells (PubMed:24623306) . Could play a role in the terminal differentiation of the intestine. Binds preferentially to methylated DNA (PubMed:28473536) .
Summary: Tissue Location: Intestinal epithelium.
Form: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Application: WB
Dilution: WB--1:1000-1:2000
Synonyms: Homeobox protein CDX-1, Caudal-type homeobox protein 1, CDX1