CDX1 Antibody (C-term) [APR32239G]

CDX1 Antibody (C-term) [APR32239G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This CDX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 236-265 amino acids from the C-terminal region of human CDX1.

Cellular Localisation: Nucleus.

Molecular Weight: 28138

Clone: Polyclonal

Gene Name: CDX1

Gene ID: 1044

Function: Plays a role in transcriptional regulation (PubMed:24623306) . Involved in activated KRAS-mediated transcriptional activation of PRKD1 in colorectal cancer (CRC) cells (PubMed:24623306) . Binds to the PRKD1 promoter in colorectal cancer (CRC) cells (PubMed:24623306) . Could play a role in the terminal differentiation of the intestine. Binds preferentially to methylated DNA (PubMed:28473536) .

Summary: Tissue Location: Intestinal epithelium.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB, IHC-P

Dilution: WB--1:1000 IHC-P--1:100~500

Synonyms: Homeobox protein CDX-1, Caudal-type homeobox protein 1, CDX1