LBD
CDX1 Antibody (C-term) [APR32239G]
- SKU:
- LBD-APR32239G
- Availability:
- Usually ships in 5 working days
Description
CDX1 Antibody (C-term) [APR32239G] | Gentaur UK, US & Europe Distribution
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This CDX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 236-265 amino acids from the C-terminal region of human CDX1.
Cellular Localisation: Nucleus.
Molecular Weight: 28138
Clone: Polyclonal
Gene Name: CDX1
Gene ID: 1044
Function: Plays a role in transcriptional regulation (PubMed:24623306) . Involved in activated KRAS-mediated transcriptional activation of PRKD1 in colorectal cancer (CRC) cells (PubMed:24623306) . Binds to the PRKD1 promoter in colorectal cancer (CRC) cells (PubMed:24623306) . Could play a role in the terminal differentiation of the intestine. Binds preferentially to methylated DNA (PubMed:28473536) .
Summary: Tissue Location: Intestinal epithelium.
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB, IHC-P
Dilution: WB--1:1000 IHC-P--1:100~500
Synonyms: Homeobox protein CDX-1, Caudal-type homeobox protein 1, CDX1