CEACAM5 Antibody | 7453

CEACAM5 Antibody | 7453 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Rat

Homology: N/A

Immunogen: CEACAM5 antibody was raised against a 15 amino acid peptide near the center of human CEACAM5.
The immunogen is located within amino acids 310 - 360 of CEACAM5 .

Research Area: Cancer, Cell Cycle

Tested Application: E, WB

Application: CEACAM5 antibody can be used for detection of CEACAM5 by Western blot at 1 - 2 μg/ml.
Antibody validated: Western Blot in rat samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Specificiy: CEACAM5 antibody is human, mouse and rat reactive. CEACAM5 antibody is predicted to not cross-react with other CEACAM protein family members.

Positive Control 1: Cat. No. 1462 - Rat Lung Tissue Lysate

Positive Control 2: Cat. No. 10-101 - Human Lung Tissue Slide

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Predicted: 77 kDa
Observed: 80kDa

Validation: N/A

Isoform: N/A

Purification: CEACAM5 Antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: CEACAM5 Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: CEACAM5 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.

Alternate Name: CEACAM5 Antibody : CEA, CD66e, CEA, Carcinoembryonic antigen-related cell adhesion molecule 5, Carcinoembryonic antigen

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: CEACAM5 is a member of the carcinoembryonic antigen (CEA) family, which belongs to the immunoglobulin superfamily (1, 2) . CEACAM proteins are involved in cell-cell recognition and modulate cellular processes that range from the shaping of tissue architecture and neovascularization to the regulation of insulin homeostasis and T-cell proliferation (2) . CEACAM5 has been shown to be overexpressed in a majority of carcinomas and has been suggested to be a intercellular adhesion molecule involved in cancer invasion and metastasis (3) .