CECR5 Polyclonal Antibody | E-AB-17786

CECR5 Polyclonal Antibody | E-AB-17786 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: A930002G03Rik, Cat eye syndrome chromosome region, candidate 5, Cat eye syndrome chromosome region, candidate 5 homolog, Cat eye syndrome critical region protein 5, Cecr5, CECR5, MGC25951, OTTMUSP00000025905

Application: WB, ELISA

Reactivity: Human

Host: Rabbit

Isotype: IgG

Reserch Areas: Cell Biology

Background: Adenosine deaminase is an enzyme that is present in most tissues and exists predominantly as a monomer, although in some tissues it is associated with adenosine deaminase-binding protein. Adenosine deaminase degrades extracellular adenosine, which is toxic for lymphocytes. A novel family of growth factors that share sequence similarity to adenosine deaminase has been identified. The cat eye syndrome critical region protein (CECR) family includes CECR1, CECR2, CECR3, CECR4, CECR5, CECR6, CECR7, CECR8 and CECR9. The genes encoding CECR proteins are candidates for Cat Eye Syndrome (CES), a developmental disorder associated with the duplication of a 2 Mb region of 22q11.2. CES is characterized by the combination of coloboma of the iris and anal atresia with fistula, downslanting palpebral fissures, preauricular tags and/or pits, frequent occurrence of heart and renal malformations, and normal or near-normal mental development. CECR family members are widely expressed. Specifically, CECR1 has the highest expression in adult heart, lung, lymphoblasts and placenta. CECR2 is also involved in neurulation and chromatin remodeling. Mutations in the CECR2 gene result in neural tube defects.

Concentration: 1.3 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human CECR5

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: WB 1:500-1:2000, ELISA 1:5000-1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 46 kDa

Molecular Weight(Observed): Refer to figures