Celecoxib | 1574

Celecoxib is a highly selective COX-2 inhibitor and primarily inhibits prostaglandin production. Celecoxib is approximately 7.6-fold more selective for COX-2 inhibition over COX-1. This specificity allows celecoxib to reduce inflammation and pain while minimizing gastrointestinal adverse drug reactions that are common with non-selective non-steroidal anti-inflammatory drugs.

Celecoxib is a highly selective COX-2 inhibitor and primarily inhibits prostaglandin production. Celecoxib is approximately 7.6-fold more selective for COX-2 inhibition over COX-1.

1574 | Celecoxib DataSheet

Alternate Name/Synonyms: Celebrex, Celebra, Celecox, SC-58635

Appearance: Off-white solid

Formulation: N/A

CAS Number: 169590-42-5

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₇H₁₄F₃N₃O₂S

Molecular Weight: 381.37

Cell-Permeable?: Yes

Purity: ≥99%

Solubilities: DMSO (200 mg/ml) or EtOH (100 mg/ml)

Handling: Protect from light and air

Country of Origin: USA

Tag Line: A COX-2 inhibitor

MDL Number: MFCD00941298

PubChem CID: 2662

SMILES: CC1=CC=C(C=C1)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)(F)F

InChi: InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18, 19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25)

InChi Key: RZEKVGVHFLEQIL-UHFFFAOYSA-N