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Cellubrevin polyclonal Antibody | BS90293
- SKU:
- BW-BS90293
- Availability:
- Usually ships in 5 working days
Description
Cellubrevin polyclonal Antibody | BS90293 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human, Mouse, Rat
Application: WB ICC IF IHC FC
Application Range: WB:1:500-1:2,000 ICC:1:50-1:200 IHC:1:50-1:200 FC:1:50-1:100
Background: Vesicle-associated membrane proteins, known as VAMPs, also designated synaptobrevins, include VAMP-1, VAMP-2, VAMP-3 (cellubrevin), and synaptotagmin, a protein that may function as an inhibitor of exocytosis. VAMP proteins are vesicular factors that are important components of the machinery controlling docking and/or fusion of secretory vesicles with their target membrane. Synaptosomal-associated proteins, known as SNAPs, including alpha- and gamma-SNAP, are cytoplasmic proteins that bind to a membrane receptor complex composed of VAMP, SNAP 25 and syntaxin. Pancreatic beta-cells express VAMP-2 and VAMP-3, and either one or both of these proteins selectively control Ca2+-mediated insulin secretion. In addition, VAMP-2 and VAMP-3 are expressed on GLUT4-containing vesicle membranes isolated from 3T3-Ll adipocytes and are important components of the insulin-dependent translocation of GLUT4 to the cell surface in adipocytes.
Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Specificity: Cellubrevin polyclonal Antibody detects endogenous levels of Cellubrevin protein.
Molecular Weight: 11 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: VAMP-3, CEB, VAMP3, SYB3, CEB, Cellubrevin, Synaptobrevin 3, Synaptobrevin-3, VAMP 3, VAMP-3, VAMP3, VAMP3, Vesicle associated membrane protein 3, Vesicle-associated membrane protein 3,
Immunogen: Synthetic peptide conjugated to KLH within N-terminal human Cellubrevin.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: ProA affinity purified
Pathway: