CHADL Antibody | 8423

CHADL Antibody | 8423 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: CHADL antibody was raised against a 19 amino acid peptide from near the carboxy terminus of human CHADL.
The immunogen is located within the last 50 amino acids of CHADL.

Research Area: Stem Cell, Homeostasis

Tested Application: E, WB, IHC, IF

Application: CHADL antibody can be used for the detection of CHADL by Western blot at 1 - 2 μg/mL. Antibody can also be used for Immunohistochemistry starting at 5 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Specificiy: CHADL antibody is human, mouse and rat reactive. CHADL antibody is predicted to not cross-react with Chondroadherin protein.

Positive Control 1: Cat. No. 1467 - Rat Skeletal Muscle Tissue Lysate

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Predicted: 84 kDa
Observed: 86 kDa

Validation: N/A

Isoform: N/A

Purification: CHADL Antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: CHADL Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: CHADL antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.

Alternate Name: Chondoadherin-like protein, SLRR4B

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The Chondroadherin-like (CHADL) protein, also known as SLRR4B, is homologous to the Chondroadherin protein and is expressed cartillaginous tissues (1) . Like Chondroadherin, CHADL belongs to the small leucine-rich proteoglycan (SLRP) family and class IV subfamily and plays a significant role in the regulation of chondrocyte growth and proliferation (1, 2) . CHADL is thought to play a negative regualtory role in collagen fibrillogenesis and chondrocyte differentiation (1) .