ChAT Polyclonal Antibody | BS65860

ChAT Polyclonal Antibody | BS65860 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat,

Application: IHC-P,

Application Range: IHC-P=1:100-500

Background: This gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform. [provided by RefSeq, May 2010].

Storage & Stability: Store at 4°C short term. Aliquot and store at -33°C long term. Avoid freeze-thaw cycles.

Specificity: ChAT Polyclonal Antibody detects endogenous levels of ChAT protein.

Molecular Weight: ~82kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Choline O acetyltransferase; Choline O acetyltransferase; Acetyl CoA choline O acetyltransferase; Acetyl CoA:choline O acetyltransferase; ChAT; CHOACTase; Choline acetylase; choline acetyltransferase; CMS1A; CMS1A2; EC 2.3.1.6; OTTHUMP00000019583; OTTHUMP00000019584; CLAT_HUMAN.

Immunogen: KLH conjugated synthetic peptide derived from human ChAT:451-550/748

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: affinity purified by Protein A

Pathway: