CHCHD7 Antibody | 7143

CHCHD7 Antibody | 7143 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: Predicted species reactivity based on immunogen sequence: Bovine: (71%)

Immunogen: Rabbit polyclonal CHCHD7 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human CHCHD7.
The immunogen is located within the last 50 amino acids of CHCHD7.

Research Area: Cancer, Cell Cycle

Tested Application: E, WB

Application: CHCHD7 antibody can be used for detection of CHCHD7 by Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in rat samples. All other applications and species not yet tested.

Specificiy: Three alternatively spliced transcript variants have been observed. CHCHD7 is predicted to not cross-react to other members of the CHCHD family.

Positive Control 1: Cat. No. 1464 - Rat Liver Tissue Lysate

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Predicted: 11 kDa

Validation: N/A

Isoform: N/A

Purification: CHCHD7 Antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: CHCHD7 Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: CHCHD7 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.

Alternate Name: CHCHD7 Antibody: COX23, Coiled-coil-helix-coiled-coil-helix domain-containing protein 7

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: CHCHD7 Antibody: CHCHD7 is a newly identified member of a multifamily of proteins containing a conserved (coiled coil 1) - (helix 1) - (coiled coil 2) - (helix 2) domain. Northern blot analysis revealed that the gene is ubiquitously expressed. Its biological function is unknown and the gene has hitherto not been associated with neoplasia. CHCHD7 and PLAG1 are located head-to-head about 500 bp apart in 8q12. A chromosomal aberration involving CHCHD7 is found in salivary gland pleiomorphic adenomas, the most common benign epithelial tumors of the salivary gland.