LBD
CHD3 Antibody (N-Term) [ApR04924G]
- SKU:
- LBD-ApR04924G
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Description
CHD3 Antibody (N-Term) [ApR04924G] | Gentaur UK, US & Europe Distribution
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This CHD3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 595-629 amino acids from human CHD3.
Cellular Localisation: Nucleus, PML body. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Associates with centrosomes in interphase and mitosis.
Molecular Weight: 226592
Clone: Polyclonal
Gene Name: CHD3
Gene ID: 1107
Function: Component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin by deacetylating histones (PubMed:9804427, PubMed:30397230) . Involved in transcriptional repressiobn as part of the NuRD complex (PubMed:27068747) . Required for anchoring centrosomal pericentrin in both interphase and mitosis, for spindle organization and centrosome integrity (PubMed:17626165) .
Summary: Tissue Location: Widely expressed..
Form: N/A
Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Application: WB
Dilution: WB--1:1000-1:2000
Synonyms: Chromodomain-helicase-DNA-binding protein 3, CHD-3, ATP-dependent helicase CHD3, Mi-2 autoantigen 240 kDa protein, Mi2-alpha, Zinc finger helicase, hZFH, CHD3