CHD3 Antibody (N-Term) [ApR04924G]

CHD3 Antibody (N-Term) [ApR04924G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This CHD3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 595-629 amino acids from human CHD3.

Cellular Localisation: Nucleus, PML body. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Associates with centrosomes in interphase and mitosis.

Molecular Weight: 226592

Clone: Polyclonal

Gene Name: CHD3

Gene ID: 1107

Function: Component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin by deacetylating histones (PubMed:9804427, PubMed:30397230) . Involved in transcriptional repressiobn as part of the NuRD complex (PubMed:27068747) . Required for anchoring centrosomal pericentrin in both interphase and mitosis, for spindle organization and centrosome integrity (PubMed:17626165) .

Summary: Tissue Location: Widely expressed..

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000-1:2000

Synonyms: Chromodomain-helicase-DNA-binding protein 3, CHD-3, ATP-dependent helicase CHD3, Mi-2 autoantigen 240 kDa protein, Mi2-alpha, Zinc finger helicase, hZFH, CHD3