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CHIR-090 | B1852

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SKU:
26-B1852-GEN
Availability:
Usually shipped in 5 working days
$1,470.00 - $3,934.00

Description

CHIR-090 is a potent, low, tight-binding inhibitor of LpxC (UDP-3-O-[(R)-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase) (Ki = 4.0 nM). Antibacterial agent

CHIR-090 is a potent, low, tight-binding inhibitor of LpxC (UDP-3-O-[(R)-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase) (Ki = 4.0 nM). Antibacterial agent

B1852 | CHIR-090 DataSheet

Alternate Name/Synonyms: N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-4-[2-[4-(morpholin-4-ylmethyl)phenyl]ethynyl]benzamide

Appearance: Crystalline solid

Formulation: N/A

CAS Number: 728865-23-4

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: N/A

Molecular Formula: C₂₄H₂₇N₃O5

Molecular Weight: 437.5

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (>20 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent, low, tight-binding inhibitor of LpxC

MDL Number: N/A

PubChem CID: 11546620

SMILES: CC(C(C(=O)NO)NC(=O)C1=CC=C(C=C1)C#CC2=CC=C(C=C2)CN3CCOCC3)O

InChi: InChI=1S/C24H27N3O5/c1-17(28)22(24(30)26-31)25-23(29)21-10-8-19(9-11-21)3-2-18-4-6-20(7-5-18)16-27-12-14-32-15-13-27/h4-11,17,22,28,31H,12-16H2,1H3,(H,25,29)(H,26,30)/t17-,22+/m1/s1

InChi Key: FQYBTYFKOHPWQT-VGSWGCGISA-N

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Additional Information

Storage Condition:
-20°C
Shipping Condition:
Gel Pack
Shelf Life:
36 months
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