BW
ChoKB (E324) polyclonal Antibody | BS2377
- SKU:
- BW-BS2377
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- Usually ships in 5 working days
Description
ChoKB (E324) polyclonal Antibody | BS2377 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: IHC
Application Range: IHC: 1:50~1:200
Background: The major pathway for the biosynthesis of phosphatidylcholine occurs via the CDP-choline pathway. Choline kinase, the initial enzyme in the sequence, plays a role in cell growth proliferation. A related protein, ChoKB (also, known as choline kinase beta), is a 395 amino acid enzyme that catalyzes the phosphorylation of choline by ATP in the presence of magnesium, thereby yielding phosphocholine and ADP. Like all choline kinases, ChoKB possesses ethanoalamine kinase activity and catalyzes the phosphorylation of ethanolamine. The gene encoding ChoKB is located less than 1 kb upstream of the CPT1B gene, suggesting that the ChoKB gene may regulate transcription CPT1B. In mice, mutations and/or deletions in the gene encoding ChoKB are the cause of hindlimb muscular dystrophy and neonatal bone deformity.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: ChoKB (E324) polyclonal Antibody detects endogenous levels of ChoKB protein.
Molecular Weight: ~ 45 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Choline/ethanolamine kinase; Choline kinase beta; Short name=CK; CKB; Choline kinase-like protein; Ethanolamine kinase; Short name=EK; Ethanolamine kinase beta; EKB; choline/ethanolamine kinase beta; CKEKB; CHKB; CHETK; CHKL
Immunogen: Synthetic peptide, corresponding to amino acids 300-342 of Human ChoKB.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: