CHR2797 | 2720

CHR2797 is a novel metalloenzyme inhibitor. It inhibits proliferation, and induces growth arrest and apoptosis in myeloma cells, including cells resistant to conventional chemotherapeutics.

CHR2797 is a novel metalloenzyme inhibitor. It inhibits proliferation, and induces growth arrest and apoptosis in myeloma cells, including cells resistant to conventional chemotherapeutics.

2720 | CHR2797 DataSheet

Alternate Name/Synonyms: alpha-[[(2R)-2-[(1S)-1-Hydroxy-2-(hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]amino]benzeneacetic acid cyclopentyl ester; Tosedostat

Appearance: Crystalline solid

Formulation: N/A

CAS Number: 238750-77-1

Structure Available?: Y

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₁H₃₀N₂O₆

Molecular Weight: 406.5

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A metalloenzyme inhibitor

MDL Number: N/A

PubChem CID: 15547703

SMILES: CC(C)CC(C(C(=O)NO)O)C(=O)NC(C1=CC=CC=C1)C(=O)OC2CCCC2

InChi: InChI=1S/C21H30N2O6/c1-13(2)12-16(18(24)20(26)23-28)19(25)22-17(14-8-4-3-5-9-14)21(27)29-15-10-6-7-11-15/h3-5,8-9,13,15-18,24,28H,6-7,10-12H2,1-2H3,(H,22,25)(H,23,26)/t16-,17+,18+/m1/s1

InChi Key: FWFGIHPGRQZWIW-SQNIBIBYSA-N