Description
CHR2797 is a novel metalloenzyme inhibitor. It inhibits proliferation, and induces growth arrest and apoptosis in myeloma cells, including cells resistant to conventional chemotherapeutics.
CHR2797 is a novel metalloenzyme inhibitor. It inhibits proliferation, and induces growth arrest and apoptosis in myeloma cells, including cells resistant to conventional chemotherapeutics.
Alternate Name/Synonyms: alpha-[[(2R)-2-[(1S)-1-Hydroxy-2-(hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]amino]benzeneacetic acid cyclopentyl ester; Tosedostat
Appearance: Crystalline solid
Formulation: N/A
CAS Number: 238750-77-1
Structure Available?: Y
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₁H₃₀N₂O₆
Molecular Weight: 406.5
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A metalloenzyme inhibitor
MDL Number: N/A
PubChem CID: 15547703
SMILES: CC(C)CC(C(C(=O)NO)O)C(=O)NC(C1=CC=CC=C1)C(=O)OC2CCCC2
InChi: InChI=1S/C21H30N2O6/c1-13(2)12-16(18(24)20(26)23-28)19(25)22-17(14-8-4-3-5-9-14)21(27)29-15-10-6-7-11-15/h3-5,8-9,13,15-18,24,28H,6-7,10-12H2,1-2H3,(H,22,25)(H,23,26)/t16-,17+,18+/m1/s1
InChi Key: FWFGIHPGRQZWIW-SQNIBIBYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |