CHST12 Antibody (N-term) [APR15429G]

CHST12 Antibody (N-term) [APR15429G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This CHST12 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 72-106 amino acids from the N-terminal region of human CHST12.

Cellular Localisation: Golgi apparatus membrane; Single- pass type II membrane protein

Molecular Weight: 48414

Clone: Polyclonal

Gene Name: CHST12

Gene ID: 55501

Function: Catalyzes the transfer of sulfate to position 4 of the N- acetylgalactosamine (GalNAc) residue of chondroitin and desulfated dermatan sulfate. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Activity toward partially desulfated dermatan sulfate is however lower. Does not form 4, 6-di-O- sulfated GalNAc when chondroitin sulfate C is used as an acceptor.

Summary: Tissue Location: Widely expressed. Expressed a high level in spinal chord, heart, spleen, thyroid, pituitary gland, adrenal gland, peripheral blood leukocytes, thymus, lung, small intestine, fetal kidney, fetal spleen and fetal lung.

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB, IHC-P

Dilution: IHC-P--1:100~500 WB--1:2000

Synonyms: Carbohydrate sulfotransferase 12, Chondroitin 4-O-sulfotransferase 2, Chondroitin 4-sulfotransferase 2, C4ST-2, C4ST2, Sulfotransferase Hlo, CHST12