Ciclopirox | B2079

Ciclopirox is a synthetic, broad-spectrum antifungal agent with additional antibacterial and anti-inflammatory activities. Ciclopirox exerts its action by binding to and chelating trivalent cations, such as Fe³⁺ and Al³⁺, thereby inhibiting the availability of essential co-factors for enzymes. In addition, ciclopirox exerts its anti-inflammatory activity by inhibiting 5-lipoxygenase and cyclooxygenase (COX). Ciclopirox also increases the activity of hypoxia-inducible factors HIF-1α and HIF-1β.

Ciclopirox is a synthetic, broad-spectrum antifungal agent with additional antibacterial and anti-inflammatory activities. Ciclopirox exerts its action by binding to and chelating trivalent cations, such as Fe³⁺ and Al³⁺, thereby inhibiting the availability of essential co-factors for enzymes. In addition, ciclopirox exerts its anti-inflammatory activity by inhibiting 5-lipoxygenase and cyclooxygenase (COX). Ciclopirox also increases the activity of hypoxia-inducible factors HIF-1α and HIF-1β.

B2079 | Ciclopirox DataSheet

Alternate Name/Synonyms: 6-Cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridinone

Appearance: White to pale yellow solid

Formulation: N/A

CAS Number: 29342-05-0

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₂H₁₇NO₂

Molecular Weight: 207.27

Cell-Permeable?: Yes

Purity: ≥98% by titration

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A synthetic, broad-spectrum antifungal agent

MDL Number: MFCD00599441

PubChem CID: 2749

SMILES: CC1=CC(=O)N(C(=C1)C2CCCCC2)O

InChi: InChI=1S/C12H17NO2/c1-9-7-11(13(15)12(14)8-9)10-5-3-2-4-6-10/h7-8,10,15H,2-6H2,1H3

InChi Key: SCKYRAXSEDYPSA-UHFFFAOYSA-N