CID-2011756 | 2607

Cell-permeable. CID-2011756 is an ATP-competitive protein kinase D (PKD) inhibitor with IC₅₀ values of 0.6, 0.7 and 3.2 μM for PKD2, PKD3 and PKD1 respectively. Inhibits phorbol ester-induced endogenous PKD1 activation in LNCaP prostate cancer cells.

CID-2011756 is an ATP-competitive protein kinase D (PKD) inhibitor with IC₅₀ values of 0.6, 0.7 and 3.2 μM for PKD2, PKD3 and PKD1 respectively. Inhibits phorbol ester-induced endogenous PKD1 activation in LNCaP prostate cancer cells.

2607 | CID-2011756 DataSheet

Alternate Name/Synonyms: 5-(3-Chlorophenyl)-N-[4-(4-morpholinylmethyl)phenyl]-2-furancarboxamide

Appearance: Off-white solid

Formulation: N/A

CAS Number: 638156-11-3

Structure Available?: Y

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₂H₂₁ClN₂O₃

Molecular Weight: 396.87

Cell-Permeable?: Yes

Purity: >98% by HPLC

Solubilities: DMSO (~ 18 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A protein kinase D (PKD) inhibitor

MDL Number: MFCD04094273

PubChem CID: 2011756

SMILES: C1COCCN1CC2=CC=C(C=C2)NC(=O)C3=CC=C(O3)C4=CC(=CC=C4)Cl

InChi: nChI=1S/C22H21ClN2O3/c23-18-3-1-2-17(14-18)20-8-9-21(28-20)22(26)24-19-6-4-16(5-7-19)15-25-10-12-27-13-11-25/h1-9,14H,10-13,15H2,(H,24,26)

InChi Key: XQJWTJLJEYIUDZ-UHFFFAOYSA-N