Additional Information
Short Description: |
PKD kinase inhibitor |
Research Area: |
Cell Signaling, Cancer, Apoptosis, Cancer Growth Inhibitors, Tyrosine Kinase Inhibitors |
Alternative Name(s): |
CID-2011756, 5-(3-Chlorophenyl)-N-[4-(morpholin-4-ylmethyl)phenyl]furan-2-carboxamide |
Category: |
Small Molecules |
Product Type: |
Inhibitor |
CAS No.: |
638156-11-3 |
Molecular Formula: |
C22H21ClN2O3 |
Molecular Weight: |
396,9 |
Source: |
Synthetic |
Purity: |
≥98% (HPLC) |
Solubility: |
Soluble to 50 mM in DMSO |
Appearance: |
White to beige solid |
Storage: |
-20ºC |
Shipping: |
Shipped Ambient |
SMILES: |
C1COCCN1CC2=CC=C(C=C2)NC(=O)C3=CC=C(O3)C4=CC(=CC=C4)Cl |
InChI: |
InChI=1S/C22H21ClN2O3/c23-18-3-1-2-17(14-18)20-8-9-21(28-20)22(26)24-19-6-4-16(5-7-19)15-25-10-12-27-13-11-25/h1-9,14H,10-13,15H2,(H,24,26) |
InChIKey: |
XQJWTJLJEYIUDZ-UHFFFAOYSA-N |
Field of Use: |
For in vitro research use only. |
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CID-2011756 | 2607
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Cell-permeable. CID-2011756 is an ATP-competitive protein kinase D (PKD) inhibitor with IC₅₀ values of 0.6, 0.7 and 3.2 μM for PKD2, PKD3 and PKD1 respectively. Inhibits phorbol ester-induced...
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