CIRBP / Cold-inducible RNA-binding protein, human recombinant | 7589

CIRBP, also known as cold-inducible RNA-binding protein, plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. CIRBP responds to a wide array of cellular stresses, including short wavelength ultraviolet light (UVC), at the transcriptional and post-translational level. It acts as a translational activator. CIRBP can bind the 3'untranslated region of specific transcripts to stabilize them and facilitate their transport to ribosomes for translation. CIRBP affects NF-B signaling as opposed to IL1B mRNA stability directly.

7589 | CIRBP / Cold-inducible RNA-binding protein human recombinant DataSheet

Biomolecule/Target: CIRBP

Synonyms: A18HNRNP, CIRP, CIRBP

Alternates names: bone morphogenetic protein 3, Osteogenin, BMP-3A

Taglines: Plays a protective role in the genotoxic stress response

NCBI Gene ID #: 651

NCBI Gene Symbol: BMP3

Gene Source: Human

Accession #: M22491

Recombinant: Yes

Source: E. coli

Purity by SDS-PAGEs: 98%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: < 1.0 EU per g of the protein as determined by the LAL method.

Activity (Specifications/test method): N/A

Biological activity: Testing is in progress.

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 31.6 kDa

Concentration: N/A

Appearance: Lyophilized

Physical form description: Lyophilized from sterile 20 mM Tris, 500 mM NaCl, 0.25 M Imidazole, 20% glycerol.

Reconstitution Instructions: Reconstitute to a concentration of 0.1-1.0 mg/ml in HO containing BSA (50 mg BSA per 1 mg of protein). This solution can then be diluted into other aqueous buffers.

Amino acid sequence: N/A