Citarinostat | B1560

Citarinostat (ACY-241), is a potent, selective and orally available histone deacetylase 6 (HDAC6) inhibitor with IC₅₀ values of 4 nM and 76 nM for HDAC6 and HDAC3, respectively. Displays antineoplastic activity.

Citarinostat (ACY-241), is a potent, selective and orally available histone deacetylase 6 (HDAC6) inhibitor with IC₅₀ values of 4 nM and 76 nM for HDAC6 and HDAC3, respectively. Displays antineoplastic activity.

B1560 | Citarinostat DataSheet

Alternate Name/Synonyms: 2-((2-chlorophenyl)(phenyl)amino)-N-(7-(hydroxyamino)-7-oxoheptyl)pyrimidine-5-carboxamide; ACY-241

Appearance: Crystalline solid

Formulation: N/A

CAS Number: 1316215-12-9

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: N/A

Molecular Formula: C₂₄H₂₆ClN₅O₃

Molecular Weight: 467.95

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (>30 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent, selective and orally available histone deacetylase 6 (HDAC6) inhibitor

MDL Number: N/A

PubChem CID: 53340426

SMILES: C1=CC=C(C=C1)N(C2=CC=CC=C2Cl)C3=NC=C(C=N3)C(=O)NCCCCCCC(=O)NO

InChi: InChI=1S/C24H26ClN5O3/c25-20-12-7-8-13-21(20)30(19-10-4-3-5-11-19)24-27-16-18(17-28-24)23(32)26-15-9-2-1-6-14-22(31)29-33/h3-5,7-8,10-13,16-17,33H,1-2,6,9,14-15H2,(H,26,32)(H,29,31)

InChi Key: VLIUIBXPEDFJRF-UHFFFAOYSA-N