Description
Citarinostat (ACY-241), is a potent, selective and orally available histone deacetylase 6 (HDAC6) inhibitor with IC₅₀ values of 4 nM and 76 nM for HDAC6 and HDAC3, respectively. Displays antineoplastic activity.
Citarinostat (ACY-241), is a potent, selective and orally available histone deacetylase 6 (HDAC6) inhibitor with IC₅₀ values of 4 nM and 76 nM for HDAC6 and HDAC3, respectively. Displays antineoplastic activity.
B1560 | Citarinostat DataSheet
Alternate Name/Synonyms: 2-((2-chlorophenyl)(phenyl)amino)-N-(7-(hydroxyamino)-7-oxoheptyl)pyrimidine-5-carboxamide; ACY-241
Appearance: Crystalline solid
Formulation: N/A
CAS Number: 1316215-12-9
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: N/A
Molecular Formula: C₂₄H₂₆ClN₅O₃
Molecular Weight: 467.95
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (>30 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A potent, selective and orally available histone deacetylase 6 (HDAC6) inhibitor
MDL Number: N/A
PubChem CID: 53340426
SMILES: C1=CC=C(C=C1)N(C2=CC=CC=C2Cl)C3=NC=C(C=N3)C(=O)NCCCCCCC(=O)NO
InChi: InChI=1S/C24H26ClN5O3/c25-20-12-7-8-13-21(20)30(19-10-4-3-5-11-19)24-27-16-18(17-28-24)23(32)26-15-9-2-1-6-14-22(31)29-33/h3-5,7-8,10-13,16-17,33H,1-2,6,9,14-15H2,(H,26,32)(H,29,31)
InChi Key: VLIUIBXPEDFJRF-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |