Description
CK-19 Monoclonal Antibody | E-AB-70231 | Gentaur UK, US & Europe Distribution
Type: Monoclonal Antibody
Synonyms: 40 kDa keratin intermediate filament, CK 19, CK-19, CK19, Cytokeratin 19, Cytokeratin-19, K19, K1C19, K1CS, Keratin 19, Keratin type I 40 kD, Keratin type I 40kD, Keratin type I cytoskeletal 19, Keratin, type I cytoskeletal 19, Keratin, type I, 40 kd, Keratin-19, KRT19, MGC15366
Application: IHC
Reactivity: Mouse, Rat
Host: Mouse
Isotype: IgG
Reserch Areas: Cancer, Signal Transduction
Background: The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells. KRT19, one of type I keratins, is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. Due to its high sensitivity, KRT19 is the most used marker for detection of tumor cells disseminated in lymph nodes, peripheral blood, and bone marrow of breast cancer patients. This antibody, generated against full length KRT19 protein, also recognizes KRT17, another type I keratin homologous to KRT19. KRT17 is used as a marker for trauma.
Concentration: 1.1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse Cytokeratin 19
Buffer: PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4
Purification Method: Affinity purification
Dilution: IHC 1:500-1:2000
Clone: 6D6G12
Conjugation: Unconjugated
Molecular Weight(Calculated): N/A
Molecular Weight(Observed): N/A