BW
Cleaved-Cathepsin O (L108) polyclonal Antibody | BS9350
- SKU:
- BW-BS9350
- Availability:
- Usually ships in 5 working days
Description
Cleaved-Cathepsin O (L108) polyclonal Antibody | BS9350 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human,Rat
Application: WB
Application Range: WB: 1:500~1:1000
Background: The cathepsin family of proteolytic enzymes contains several diverse classes of proteases. The cysteine protease class comprises cathepsins B, L, H, K, S, and O. The aspartyl protease class is composed of cathepsins D and E. Cathepsin G is in the serine protease class. Most cathepsins are lysosomal and each is involved in cellular metabolism, participating in various events such as peptide biosynthesis and protein degradation. Cathepsin O maintains the structural features characteristic of other cysteine proteinases including the active site cysteine residue that is involved in covalent intermediate formation during peptide hydrolysis. Cathepsin O is an endoproteinase that may be involved in extracellular matrix degradation. Cathepsin O is abundantly expressed in the ovary, kidney and placenta with lower levels found in thymus and skeletal muscle.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: Cleaved-Cathepsin O (L108) polyclonal Antibody detects endogenous levels of Cleaved-Cathepsin O protein.
Molecular Weight: ~ 23 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Cathepsin O; CTSO; CTSO1
Immunogen: Synthetic peptide, corresponding to amino acids 108-321 of Human Cleaved-Cathepsin O.
Conjugate: Unconjugated
Modification: Cleaved
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: