Clinical Chemistry HBP Reagent Kit

The Axis-Shield Heparin Binding Protein (HBP) test is an immunoturbidimetric assay for the quantitative determination of Heparin Binding Protein in human plasma. The assay is intended for use in conjunction with other laboratory findings and clinical assessments as an aid in the assessment for the presence of organ dysfunction, or risk of progression to organ dysfunction within 72 hours, in patients presenting to the Emergency Department (ED) with suspected infection.

Part Number: FHHBP101

Method: Latex immunoturbidimetry

Description: Two liquid-stable reagents, 6 calibrators, 2 controls

• Easy-to-use clinical chemistry assay, readily adaptable to many chemistry analysers
• Early identification of patients at risk of developing severe sepsis
• Published data shows improved performance over existing biomarkers

Assay Principle

The determination of HBP is based on a turbidimetric reaction which occurs between circulating HBP and avian monospecific polyclonal antibodies bound to chloromethyl microparticles at optimal pH conditions in the presence of polyethylene glycol polymer (PEG). The magnitude of the change is proportional to the quantity of HBP in the test sample.

Clinical Chemistry HBP Reagent Kit IFU