CNRIP1 Antibody | 7303

CNRIP1 Antibody | 7303 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: Predicted species reactivity based on immunogen sequence: Bovine: (93%)

Immunogen: CNRIP1 antibody was raised against a 15 amino acid peptide near the center of human CNRIP1.
The immunogen is located within amino acids 50 - 100 of CNRIP1.

Research Area: Neuroscience

Tested Application: E, WB, IHC-P, IF

Application: CNRIP1 antibody can be used for detection of CNRIP1 by Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

Specificiy: At least two isoforms of CNRIP1 are known to exist; this antibody will detect both isoforms.

Positive Control 1: Cat. No. 1303 - Human Brain Tissue Lysate

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Predicted: 18 kDa
Observed: 16 kDa

Validation: N/A

Isoform: N/A

Purification: CNRIP1 Antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: CNRIP1 Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: CNRIP1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.

Alternate Name: CNRIP1 Antibody: CRIP1, C2orf32, CB1 cannabinoid receptor-interacting protein 1, CRIP-1

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: CNRIP1 Antibody: The CNRIP1 (cannabinoid receptor interacting protein 1) protein is a G-protein coupled receptor which interacts with the C-terminal tail of cannabinoid receptor 1 (CB1) and is thought to play a role in synaptic plasticity, analgesia, appetite, and neuroprotection. One isoform of CNRIP1, CNRIP1a, modulates the constitutive CB1 receptor activity in the central nervous system (CNS) , while the role of the shorter isoform CNRIP1b is yet unknown. CNRIP1 has been suggested as a potential target for CNS drug discovery.