CNX-1351 | B1673

CNX1351 is a potent and selective inhibitor of PI3Kα with IC50 value of 6.8 nM

CNX1351 is a potent and selective inhibitor of PI3Kα with IC50 value of 6.8 nM

B1673 | CNX-1351 DataSheet

Alternate Name/Synonyms: CNX-1351; CNX1351; CNX 1351; 1-(4-((2-(1H-indazol-4-yl)-4-morpholinothieno[3,2-d]pyrimidin-6-yl)methyl)piperazin-1-yl)-6-methylhept-5-ene-1,4-dione

Appearance: Solid

Formulation: N/A

CAS Number: 1276105-89-5

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₃₀H₃₅N₇O₃S

Molecular Weight: 573.71

Cell-Permeable?: Yes

Purity: >98%

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent and selective PI3Kα inhibitor

MDL Number: N/A

PubChem CID: 58441401

SMILES: CC(=CC(=O)CCC(=O)N1CCN(CC1)CC2=CC3=C(S2)C(=NC(=N3)C4=C5C=NNC5=CC=C4)N6CCOCC6)C

InChi: InChI=1S/C30H35N7O3S/c1-20(2)16-21(38)6-7-27(39)36-10-8-35(9-11-36)19-22-17-26-28(41-22)30(37-12-14-40-15-13-37)33-29(32-26)23-4-3-5-25-24(23)18-31-34-25/h3-5,16-18H,6-15,19H2,1-2H3,(H,31,34)

InChi Key: DLNUPKDFXMWRFP-UHFFFAOYSA-N