Description
cofilin1 / cofilin2 (phospho Tyr88) Antibody | 79-240 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human, Mouse
Homology: N/A
Immunogen: cofilin1/cofilin2 (phospho-Tyr88) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 88 (A-T-Y (p) -E-T) derived from Human coflin1/cofilin2.
Research Area: Phospho-Specific
Tested Application: IHC, WB
Application: Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Specificiy: This antibody detects endogenous level of cofilin1/cofilin2 only when phosphorylated at tyrosine 88.
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: 19 kDa
Validation: N/A
Isoform: N/A
Purification: Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Clonality: Polyclonal
Clone: N/A
Isotype: N/A
Conjugate: Unconjugated
Physical State: Liquid
Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+) , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration: 1 mg/mL
Storage Condition: Store antibody at -20˚C for up to one year.
Alternate Name: CFL, HEL-S-15, ESR, NR3A1, CFL1/CFL2
User Note: N/A
BACKGROUND: Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods.