COL6A2 (Y711) polyclonal Antibody | BS2181

COL6A2 (Y711) polyclonal Antibody | BS2181 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Application: WB IHC

Application Range: WB: 1:500~1:1000 IHC: 1:50~1:200

Background: Collagens (COLs) are fibrous, extracellular matrix proteins with high tensile strength that function as the major components of connective tissue, such as tendons and cartilage. All COL proteins contain a triple helix domain and frequently show lateral self-association in order to form complex connective tissues. Existing as a trimer with two other type VI alpha proteins, COL6A2 acts as a cell-binding protein that plays an important role in the organization of matrix components. Defects in the gene encoding COL6A2 are associated with Bethlem myopathy (BM) and Ullrich congenital muscular dystrophy (UCMD) . Multiple isoforms of COL6A2 exist due to alternative splicing events.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: COL6A2 (Y711) polyclonal Antibody detects endogenous levels of COL6A2 protein.

Molecular Weight: ~109 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Collagen alpha 2 (VI) chain; Collagen alpha-2 (VI) chain; Collagen VI alpha 2 polypeptide; PP3610;

Immunogen: Synthetic peptide, corresponding to amino acids 681-730 of Human COL6A2.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: