Compound 112254 | 2573

An adiponectin receptor (AdipoR) agonist. Binds to AdipoR1 and AdipoR2 less potent than AdipoRon (Cat. Nos. 2565 & 2572). Activates 5'-adenosine monophosphate-activated protein kinase (AMPK) in cultured mammalian cells .Improves diabetes, glucose and lipid metabolism and insulin sensitivity in cultured cells and in mice by AdipoR-dependent mechanisms.

Compound 112254 is a adiponectin receptor (AdipoR) agonist. Binds to AdipoR1 and AdipoR2 less potent than AdipoRon (Cat. Nos. 2565 & 2572). Activates 5'-adenosine monophosphate-activated protein kinase (AMPK) in cultured mammalian cells .Improves diabetes, glucose and lipid metabolism and insulin sensitivity.

2573 | Compound 112254 DataSheet

Alternate Name/Synonyms: 4-(tert-Butyl)-N-(3-(4-(4-methoxybenzyl)piperazin-1-yl)-3-oxopropyl)benzamide

Appearance: White solid

Formulation: N/A

CAS Number: N/A

Structure Available?: Y

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₆H₃₅N₃O₃

Molecular Weight: 437.57

Cell-Permeable?: Yes

Purity: ≥98% by NMR

Solubilities: DMSO or EtOH

Handling: Protect from air and light

Country of Origin: USA

Tag Line: An adiponectin receptor agonist

MDL Number: N/A

PubChem CID: N/A

SMILES: CC(C1=CC=C(C=C1)CNCCCN2CCN(CC3=CC=C(OC)C=C3)CC2)(C)C

InChi: InChI=1S/C26H39N3O/c1-26(2,3)24-10-6-22(7-11-24)20-27-14-5-15-28-16-18-29(19-17-28)21-23-8-12-25(30-4)13-9-23/h6-13,27H,5,14-21H2,1-4H3

InChi Key: LUEVKMSIYRYUKC-UHFFFAOYSA-N