Connexin 43 Antibody| F44391-0.08ML/F44391-0.4ML/R35389-100UG

Connexin 43 Antibody| F44391-0.08ML/F44391-0.4ML/R35389-100UG | Gentaur UK, US & Europe Distribution

Background: Gap junction protein, alpha 1 is a member of the connexin gene family and a component of gap junctions. Gap junctions are composed of arrays of intercellular channels and provide a route for the diffusion of materials of low molecular weight from cell to cell. Connexin 43 is the major protein of gap junctions in the heart, and gap junctions are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. Connexin 43 is targeted by several protein kinases that regulate myocardial cell-cell coupling. A related intron-less connexin 43 pseudogene, GJA1P, has been mapped to chromosome 5.

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Isotype: Rabbit Ig

Species Reactivity: Human, Mouse, Rat

Predicted Spacies Reactivity: Bovine, Xenopus

Application: WB, IHC, ELISA

Application Details: Western blot: 1:1000, IHC (Paraffin): 1:50-1:100

Application Note: Titration of the Connexin 43 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This Connexin 43 antibody is available for research use only.

Purity: Purified

Immunogen: A portion of amino acids 107-138 from the human protein was used as the immunogen for this Connexin 43 antibody.

Storage: Aliquot the Connexin 43 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A