LBD
Connexin 50 Antibody (C-term) [APR11635G]
- SKU:
- LBD-APR11635G
- Availability:
- Usually ships in 5 working days
Description
Connexin 50 Antibody (C-term) [APR11635G] | Gentaur UK, US & Europe Distribution
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H, M
Specificity: This Connexin 50 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 402-433 amino acids from the C-terminal region of human Connexin 50.
Cellular Localisation: Cell membrane; Multi-pass membrane protein {ECO:0000250|UniProtKB:P55917}. Cell junction, gap junction
Molecular Weight: 48229
Clone: Polyclonal
Gene Name: GJA8
Gene ID: 2703
Function: Structural component of eye lens gap junctions (PubMed:18006672, PubMed:19756179) . Gap junctions are dodecameric channels that connect the cytoplasm of adjoining cells. They are formed by the docking of two hexameric hemichannels, one from each cell membrane (By similarity) . Small molecules and ions diffuse from one cell to a neighboring cell via the central pore (PubMed:18006672, PubMed:19756179) .
Summary: Tissue Location: Eye lens..
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB, IHC-P
Dilution: WB--1:1000 IHC-P--1:100~500
Synonyms: Gap junction alpha-8 protein, Connexin-50, Cx50, Lens fiber protein MP70, GJA8