Description
Coumarin boronic acid (CBA) is a fluorescent probe useful for the detection of peroxynitrite, hypochlorous acid, and hydrogen peroxide. It reacts directly and rapidly with peroxynitrite at a much faster rate (k = 1.1 μM/s) than hydrogen peroxide (k =1.5 M/s) and moderately faster rate than hypochlorous acid. Peroxynitrite oxidizes CBA stoichiometrically at a 1:1 ratio into a fluorescent product that can be examined at an excitation of 332 nm and emission > 400 nm.
Coumarin boronic acid (CBA) is a fluorescent probe useful for the detection of peroxynitrite, hypochlorous acid, and hydrogen peroxide. It reacts directly and rapidly with peroxynitrite at a much faster rate (k = 1.1 μM/s) than hydrogen peroxide (k =1.5 M/s) and moderately faster rate than hypochlorous acid. Peroxynitrite oxidizes CBA stoichiometrically at a 1:1 ratio into a fluorescent product that can be examined at an excitation of 332 nm and emission > 400 nm.
B1029 | Coumarin Boronic acid DataSheet
Alternate Name/Synonyms: B-(2-oxo-2H-1-benzopyran-7-yl)-boronic acid; CBA
Appearance: Off-white solid
Formulation: N/A
CAS Number: 1357078-03-5
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₉H₇BO₄
Molecular Weight: 190
Cell-Permeable?: Yes
Purity: ≥98%
Solubilities: DMSO (~ 3 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A fluorescent probe useful for the detection of peroxynitrite, hypochlorous acid, and hydrogen peroxide.
MDL Number: N/A
PubChem CID: 73977909
SMILES: B(C1=CC2=C(C=C1)C=CC(=O)O2)(O)O
InChi: InChI=1S/C9H7BO4/c11-9-4-2-6-1-3-7(10(12)13)5-8(6)14-9/h1-5,12-13H
InChi Key: MUZVCJQIBNTECF-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |