CPSF3L polyclonal Antibody | BS6946

CPSF3L polyclonal Antibody | BS6946 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB IF

Application Range: WB: 1:500~1:2000 IHC: 1:50~1:200

Background: RNA polymerase II (Pol II) is an enzyme that is composed of twelve subunits and is responsible for the transcription of protein-coding genes. Transcription initiation requires Pol II-mediated recruitment of transcription machinery to a target promoter, thereby allowing transcription to begin. The integrator complex is a multi-protein complex that associates with the C-terminal domain of Pol II and is involved in small nuclear RNA (snRNA) transcription and 3’-end processing. This interaction is facilitated by phosphorylation of serine-7 on Pol II. CPSF3L (Cleavage and polyadenylation-specific factor 3-like protein), also known as Integrator complex subunit 11 (INTS11), is a 600 amino acid protein that is a component of the integrator complex and is expressed as three isoforms.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: CPSF3L polyclonal Antibody detects endogenous levels of CPSF3L protein.

Molecular Weight: ~ 68 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Integrator complex subunit 11; Int11; Cleavage and polyadenylation-specific factor 3-like protein; CPSF3-like protein; Protein related to CPSF subunits of 68 kDa; RC-68; CPSF3L; INTS11; RC68

Immunogen: Recombinant full length Human CPSF3L.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: