Description
CPSF3L polyclonal Antibody | BS6946 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB IF
Application Range: WB: 1:500~1:2000 IHC: 1:50~1:200
Background: RNA polymerase II (Pol II) is an enzyme that is composed of twelve subunits and is responsible for the transcription of protein-coding genes. Transcription initiation requires Pol II-mediated recruitment of transcription machinery to a target promoter, thereby allowing transcription to begin. The integrator complex is a multi-protein complex that associates with the C-terminal domain of Pol II and is involved in small nuclear RNA (snRNA) transcription and 3’-end processing. This interaction is facilitated by phosphorylation of serine-7 on Pol II. CPSF3L (Cleavage and polyadenylation-specific factor 3-like protein), also known as Integrator complex subunit 11 (INTS11), is a 600 amino acid protein that is a component of the integrator complex and is expressed as three isoforms.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: CPSF3L polyclonal Antibody detects endogenous levels of CPSF3L protein.
Molecular Weight: ~ 68 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Integrator complex subunit 11; Int11; Cleavage and polyadenylation-specific factor 3-like protein; CPSF3-like protein; Protein related to CPSF subunits of 68 kDa; RC-68; CPSF3L; INTS11; RC68
Immunogen: Recombinant full length Human CPSF3L.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: