CRMP-3 (C132) polyclonal Antibody | BS3849

CRMP-3 (C132) polyclonal Antibody | BS3849 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: Collapsin response mediator proteins (CRMPs), including CRMP-1 (DRP-1), CRMP-2 (DRP-2 or TOAD64), CRMP-3 (DRP-4), CRMP-4 (DRP-3) and CRMP-5 (DRP-5), mediate signal transduction after exposure of neural cells to the axon guidance molecule Semaphorin 3A (SEMA3A) /collapsin. CRMPs are present in the developing cerebral cortex and neocortical neurons and are responsive to SEMA3A. In the adult brain, the expression of CRMPs is dramatically downregulated. However, they remain expressed in structures that retain their capacity for differentiation and plasticity. CRMP-3 is expressed transiently in developing spinal cord and selectively in the postnatal cerebellum.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: CRMP-3 (C132) polyclonal Antibody detects endogenous levels of CRMP-3 protein.

Molecular Weight: ~ 50 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Dihydropyrimidinase-related protein 4; DRP-4; Collapsin response mediator protein 3; CRMP-3; UNC33-like phosphoprotein 4; ULIP-4; DPYSL4; CRMP3; ULIP4

Immunogen: Synthetic peptide, corresponding to amino acids 111-160 of Human CRMP-3.

Conjugate: N/A

Modification: N/A

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: N/A