BW
CSE1L monoclonal Antibody | MB62920
- SKU:
- BW-MB62920
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- Usually ships in 5 working days
Description
CSE1L monoclonal Antibody | MB62920 | Gentaur UK, US & Europe Distribution
Host: Mouse
Reactivity: Human, Mouse, Rat
Application: IHC, WB
Application Range: WB 1:500, IHC 1:2000
Background: Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]
Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Specificity: chromosome segregation 1 like
Molecular Weight: 110.2 kDa (Predicted)
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: CAS; CSE1; XPO2
Immunogen: Human recombinant protein fragment corresponding to amino acids 1-300 of human CSE1L (NP_001307) produced in E.coli.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway: N/A