Description
CST6 is a member of the type 2 cystatin family. Some of the members are active cysteine protease inhibitors, while cystatin E/M moderate the inhibition of cathepsin B but is not active against cathepsin C. CST6 is secretable proteins that influence osteogenesis and bone resorption, regulation of the insulin and hepatocyte growth factor receptors, and the response to systemic inflammation.
9234 | CST6 human recombinant DataSheet
Biomolecule/Target: CST6
Synonyms: Cystatin-M, Cystatin E/M
Alternates names: BMP4, ZYME, BMP2B, BMP2B1
Taglines: A secretable proteins that influence osteogenesis, regulates insulin and hepatocyte growth factor receptors, and the response to systemic inflammation.
NCBI Gene ID #: 652
NCBI Gene Symbol: BMP 4
Gene Source: Human
Accession #: P12644
Recombinant: Yes
Source: E.coli
Purity by SDS-PAGEs: 98%
Assay: SDS-PAGE
Purity: 90%
Assay #2: N/A
Endotoxin Level: N/A
Activity (Specifications/test method): N/A
Biological activity: s recombinant human BMP-4 is biologically active. The ED as determined by dose-dependent induction of alkaline phosphatase activity with C2C12 cells is in the range of 2-12 µg/ml.
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 13.0 kDa
Concentration: 0.5 mg/ml
Appearance: Liquid
Physical form description: Liquid
Reconstitution Instructions: Reconstitute to a concentration of 0.1-1.0 mg/ml in sterile 20 mM acetic acid. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or 20°C for future use.
Amino acid sequence: N/A