Description
CSTA, also known as Stefin A, is thiol protease inhibitors that form complexes with papain and the cathepsins B, H and L. The protein is one of the precursor proteins of the cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance. CSTA is thought to be a tumor suppressor, since an inverse correlation seems to exist between the level of CSTA and tumor progression, in several malignancies
9236 | CSTA human recombinant DataSheet
Biomolecule/Target: CSTA
Synonyms: Cystatin-A, STF1, STFA
Alternates names: BMP4, ZYME, BMP2B, BMP2B1
Taglines: A thiol protease inhibitors that form complexes with papain and the cathepsins B, H and L
NCBI Gene ID #: 652
NCBI Gene Symbol: BMP 4
Gene Source: Human
Accession #: P12644
Recombinant: Yes
Source: E.coli
Purity by SDS-PAGEs: 98%
Assay: SDS-PAGE
Purity: >95%
Assay #2: N/A
Endotoxin Level: N/A
Activity (Specifications/test method): N/A
Biological activity: s recombinant human BMP-4 is biologically active. The ED as determined by dose-dependent induction of alkaline phosphatase activity with C2C12 cells is in the range of 2-12 µg/ml.
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 13.0 kDa
Concentration: 1 mg/ml
Appearance: Liquid
Physical form description: Liquid
Reconstitution Instructions: Reconstitute to a concentration of 0.1-1.0 mg/ml in sterile 20 mM acetic acid. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or 20°C for future use.
Amino acid sequence: N/A