CTACK, Murine Recombinant | 7128

CTACK is a keratinocyte-derived CC chemokine which signals through the CCR10 receptor. Both CTACK and CCR10 are expressed in normal and irritated epithelial cells. CTACK selectively attracts CLA+ T-cells and directs them into the skin. CTACK contains the four highly conserved cysteine residues present in most CC chemokines. The mature protein contains 88 amino acid residues. Recombinant murine CTACK is a 10.9 kDa Protein, containing 95 amino acid residues.

7128 | CTACK Murine Recombinant DataSheet

Biomolecule/Target: CTACK

Synonyms: Cutaneous T-cell Attracting Chemokine, CCL27, ALP, Skinkine, Eskine

Alternates names: Osteogenic Protein 1, BMP-7

Taglines: A keratinocyte-derived CC chemokine which signals through the CCR10 receptor

NCBI Gene ID #: 655

NCBI Gene Symbol: BMP 7

Gene Source: Murine

Accession #: P18075

Recombinant: Yes

Source: E. coli.

Purity by SDS-PAGEs: 98%

Assay: SDS-PAGE

Purity: N/A

Assay #2: HPLC

Endotoxin Level: < 0.1 ng/g of protein (<1EU/g).

Activity (Specifications/test method): Determined by its ability to chemoattract human peripheral blood lymphocytes using a concentration range of 10.0-100.0 ng/ml.

Biological activity: ’s recombinant human BMP-7 is biologically active. The ED as determined by dose-dependent induction of alkaline phosphatase activity with C2C12 cells is in the range of 2-12 µg/ml.

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 15.7 kDa

Concentration: N/A

Appearance: Lyophilized powder

Physical form description: Sterile filtered through a 0.2 micron filter. Lyophilized with no additives.

Reconstitution Instructions: Reconstitute to a concentration of 0.1-1.0 mg/ml in HO. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.

Amino acid sequence: N/A