CX-4945 | 2459

A selective, ATP-competitive, Casein kinase -2 (CK2) inhibitor (Ki = 0.38 nM). Displays potent anti-tumor activity in several cancer cell lines.

CX-4945 is a selective, ATP-competitive, Casein kinase -2 (CK2) inhibitor (Ki = 0.38 nM).

2459 | CX-4945 DataSheet

Alternate Name/Synonyms: 5-((3-chlorophenyl)amino)benzo[c][2,6]naphthyridine-8-carboxylic acid; Silmitasertib

Appearance: Yellow solid

Formulation: N/A

CAS Number: 1009820-21-6

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₉H₁₂ClN₃O₂

Molecular Weight: 349.77

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (>60 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A selective CK2 inhibitor

MDL Number: N/A

PubChem CID: 24748573

SMILES: C1=CC(=CC(=C1)Cl)NC2=C3C=CN=CC3=C4C=CC(=CC4=N2)C(=O)O

InChi: InChI=1S/C19H12ClN3O2/c20-12-2-1-3-13(9-12)22-18-15-6-7-21-10-16(15)14-5-4-11(19(24)25)8-17(14)23-18/h1-10H,(H,22,23)(H,24,25)

InChi Key: MUOKSQABCJCOPU-UHFFFAOYSA-N