Description
A selective, ATP-competitive, Casein kinase -2 (CK2) inhibitor (Ki = 0.38 nM). Displays potent anti-tumor activity in several cancer cell lines.
CX-4945 is a selective, ATP-competitive, Casein kinase -2 (CK2) inhibitor (Ki = 0.38 nM).
Alternate Name/Synonyms: 5-((3-chlorophenyl)amino)benzo[c][2,6]naphthyridine-8-carboxylic acid; Silmitasertib
Appearance: Yellow solid
Formulation: N/A
CAS Number: 1009820-21-6
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₉H₁₂ClN₃O₂
Molecular Weight: 349.77
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (>60 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A selective CK2 inhibitor
MDL Number: N/A
PubChem CID: 24748573
SMILES: C1=CC(=CC(=C1)Cl)NC2=C3C=CN=CC3=C4C=CC(=CC4=N2)C(=O)O
InChi: InChI=1S/C19H12ClN3O2/c20-12-2-1-3-13(9-12)22-18-15-6-7-21-10-16(15)14-5-4-11(19(24)25)8-17(14)23-18/h1-10H,(H,22,23)(H,24,25)
InChi Key: MUOKSQABCJCOPU-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
24 months |