CXCL12 Antibody | 7591

CXCL12 Antibody | 7591 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse

Homology: N/A

Immunogen: CXCL12 antibody was raised against a 16 amino acid peptide near the center of human CXCL12 .
The immunogen is located within the last 50 amino acids of CXCL12.

Research Area: Immunology

Tested Application: E, WB, ICC

Application: CXCL12 antibody can be used for detection of CXCL12 by Western blot at 1 - 2 μg/ml. Antibody can also be used for Immunocytochemistry starting at 5 μg/mL.
Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested.

Specificiy: CXCL12 antibody is human and mouse reactive. Multiple isoforms of CXCL12 are known to exist.

Positive Control 1: Cat. No. 1201 - HeLa Cell Lysate

Positive Control 2: Cat. No. 17-001 - HeLa Cell Slide

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Predicted: 15 kDa
Observed: 18 kDa

Validation: N/A

Isoform: N/A

Purification: CXCL12 antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: CXCL12 antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: CXCL12 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.

Alternate Name: CXCL12 Antibody: IRH, PBSF, SDF1, TLSF, TPAR1, SCYB12, SDF1A, SDF1B, Stromal cell-derived factor 1, C-X-C motif chemokine 12, SDF-1

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The CXCL12 protein, also known as SDF1, is a stromal cell-derived alpha chemokine member of the intercrine family. CXCL12 functions as the ligand for the G-protein coupled receptor, chemokine (C-X-C motif) receptor 4 (CXCR4) and CXCR7, and plays a role in many diverse cellular functions, including embryogenesis, immune surveillance, inflammation response, tissue homeostasis, and tumor growth and metastasis (reviewed in 1) . Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections (2) .