CXCL12 polyclonal Antibody | BS90348

CXCL12 polyclonal Antibody | BS90348 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Application: WB IHC FC

Application Range: WB:1:500 IHC:1:50-1:200 FC:1:50-1:100

Background: The stromal cell-derived factor 1 (SDF1), also known as C-X-C motif chemokine 12 (CXCL12), is a chemokine protein that in humans is encoded by the CXCL12 gene on chromosome 10. It is ubiquitously expressed in many tissues and cell types. Stromal cell-derived factors 1-alpha and 1-beta are small cytokines that belong to the chemokine family, members of which activate leukocytes and are often induced by proinflammatory stimuli such as lipopolysaccharide, TNF, or IL1. The chemokines are characterized by the presence of 4 conserved cysteines that form 2 disulfide bonds. They can be classified into 2 subfamilies. In the CC subfamily, the cysteine residues are adjacent to each other. In the CXC subfamily, they are separated by an intervening amino acid. The SDF1 proteins belong to the latter group. CXCL12 signaling has been observed in several cancers. The CXCL12 gene also contains one of 27 SNPs associated with increased risk of coronary artery disease.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: CXCL12 polyclonal Antibody detects endogenous levels of CXCL12 protein.

Molecular Weight: 10 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: SDF-1, hSDF-1, IRH, hIRH, PBSF, CXCL12, SDF1, SDF1A, SDF1B, 12-O-tetradecanoylphorbol 13-acetate repressed protein 1, AI174028, C-X-C motif chemokine 12, Chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1), Chemokine (C-X-C motif) ligand 12, Chemokine CXC motif ligand 12, cxcl12, hIRH, hSDF-1, Intercrine reduced in hepatomas, IRH, OTTHUMP00000019491, PBSF, Pre-B cell growth-stimulating factor, SCYB12, SDF 1, SDF-1, SDF-1-alpha (3-67), SDF-1a, SDF-1b, SDF1, SDF1A, SDF1B, Stromal cell-derived factor 1, Stromal cell-derived factor 1 delta, Stromal cell-derived factor 1 gamma, Stromal cell-derived factor 1a, Stromal cell-derived factor-1 alpha, Thymic lymphoma cell-stimulating factor, Tlsf, TLSF-a, TLSF-b, Tlsfa, Tlsfb, TPAR1,

Immunogen: Recombinant protein

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Protein affinity purified

Pathway: