Cyclo（RGDfK） | B2363

Cyclo(-RGDfK) is a potent and selective inhibitor of the αvβ3 integrin (IC₅₀ = 0.94 nM)

Cyclo(-RGDfK) is a potent and selective inhibitor of the αvβ3 integrin (IC₅₀ = 0.94 nM)

B2363 | Cyclo（RGDfK） DataSheet

Alternate Name/Synonyms: cyclo[Arg-Gly-Asp-D-Phe-Lys],2-[(2S,5R,8S,11S)-8-(4-aminobutyl)-5-benzyl-11-[3-(diaminomethylideneamino)propyl]-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentazacyclopentadec-2-yl]acetic acid

Appearance: Off-white solid

Formulation:

CAS Number: 161552-03-0

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: N/A

Molecular Formula: C₂₇H₄₁N₉O₇

Molecular Weight: 603.68

Cell-Permeable?: TRUE

Purity: ≥98% by HPLC

Solubilities: >30 mg/ml (DMSO) in 0,>50 mg/ml (H₂O) in 0

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A potent and selective αvβ3 integrin inhibitor

MDL Number:

PubChem CID: 10196873

SMILES: C1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCN=C(N)N)CCCCN)CC2=CC=CC=C2)CC(=O)O

InChi: InChI=1S/C27H41N9O7/c28-11-5-4-9-18-24(41)34-17(10-6-12-31-27(29)30)23(40)32-15-21(37)33-20(14-22(38)39)26(43)36-19(25(42)35-18)13-16-7-2-1-3-8-16/h1-3,7-8,17-20H,4-6,9-15,28H2,(H,32,40)(H,33,37)(H,34,41)(H,35,42)(H,36,43)(H,38,39)(H4,29,30,31)/t17-,18-,19+,20-/m0/s1

InChi Key: NVHPXYIRNJFKTE-HAGHYFMRSA-N