Description
Cyclo(-RGDfK) is a potent and selective inhibitor of the αvβ3 integrin (IC₅₀ = 0.94 nM)
Cyclo(-RGDfK) is a potent and selective inhibitor of the αvβ3 integrin (IC₅₀ = 0.94 nM)
B2363 | Cyclo(RGDfK) DataSheet
Alternate Name/Synonyms: cyclo[Arg-Gly-Asp-D-Phe-Lys],2-[(2S,5R,8S,11S)-8-(4-aminobutyl)-5-benzyl-11-[3-(diaminomethylideneamino)propyl]-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentazacyclopentadec-2-yl]acetic acid
Appearance: Off-white solid
Formulation:
CAS Number: 161552-03-0
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: N/A
Molecular Formula: C₂₇H₄₁N₉O₇
Molecular Weight: 603.68
Cell-Permeable?: TRUE
Purity: ≥98% by HPLC
Solubilities: >30 mg/ml (DMSO) in 0,>50 mg/ml (H₂O) in 0
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: A potent and selective αvβ3 integrin inhibitor
MDL Number:
PubChem CID: 10196873
SMILES: C1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCN=C(N)N)CCCCN)CC2=CC=CC=C2)CC(=O)O
InChi: InChI=1S/C27H41N9O7/c28-11-5-4-9-18-24(41)34-17(10-6-12-31-27(29)30)23(40)32-15-21(37)33-20(14-22(38)39)26(43)36-19(25(42)35-18)13-16-7-2-1-3-8-16/h1-3,7-8,17-20H,4-6,9-15,28H2,(H,32,40)(H,33,37)(H,34,41)(H,35,42)(H,36,43)(H,38,39)(H4,29,30,31)/t17-,18-,19+,20-/m0/s1
InChi Key: NVHPXYIRNJFKTE-HAGHYFMRSA-N
Additional Information
Storage Condition: |
-20ºC |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |