CYP11B2 Polyclonal Antibody | E-AB-17738

CYP11B2 Polyclonal Antibody | E-AB-17738 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: ALDOS, Aldosterone synthase, Aldosterone-synthesizing enzyme, C11B2, CYP11B2, CYPXIB2, Cytochrome P-450Aldo, Cytochrome P-450C18, Cytochrome P450 11B2, Cytochrome P450 11B2, mitochondrial, mitochondrial, P-450Aldo, P-450C18, Steroid 18-hydroxylase

Application: WB, IHC, ELISA

Reactivity: Human

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Cardiovascular, Metabolism

Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane. The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity. Mutations in this gene cause corticosterone methyl oxidase deficiency.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human CYP11B2

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:5000-1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 58 kDa

Molecular Weight(Observed): Refer to figures