CYP1A1 Antibody| F40404-0.08ML/F40404-0.4ML/F50939-0.05ML/F50939-0.2ML/R31887

CYP1A1 Antibody| F40404-0.08ML/F40404-0.4ML/F50939-0.05ML/F50939-0.2ML/R31887 | Gentaur UK, US & Europe Distribution

Background: This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15.

Format: Purified

Clone: 655CT6.1.2

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Isotype: Mouse IgG1

Species Reactivity: Human

Predicted Spacies Reactivity: Primate

Application: WB, ELISA

Application Details: Western blot: 1:100-1:1000

Application Note: Titration of the CYP1A1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This CYP1A1 antibody is available for research use only.

Purity: Purified

Immunogen: A portion of amino acids 377-405 from the human protein was used as the immunogen for this CYP1A1 antibody.

Storage: Aliquot the CYP1A1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A