BW
CYP39A1 polyclonal Antibody | BS62104
- SKU:
- BW-BS62104
- Availability:
- Usually ships in 5 working days
Description
CYP39A1 polyclonal Antibody | BS62104 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human,Rat,Mouse
Application: WB
Application Range: WB: 1:500~1:1000
Background: 24-hydroxycholesterol 7-alpha-hydroxylase, a cytochrome P450 monooxygenase involved in neural cholesterol clearance through bile acid synthesis (PubMed:25201972, PubMed:10748047) . Catalyzes 7-alpha hydroxylation of (24S) -hydroxycholesterol, a neural oxysterol that is metabolized to bile acids in the liver (PubMed:25201972, PubMed:10748047) . Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: CYP39A1 polyclonal Antibody detects endogenous levels of CYP39A1 protein.
Molecular Weight: ~ 55 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: 24-hydroxycholesterol 7-alpha-hydroxylase; Cytochrome P450 39A1; hCYP39A1; Oxysterol 7-alpha-hydroxylase; CYP39A1
Immunogen: Synthetic peptide, corresponding to Human CYP39A1.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 96% (by SDS-PAGE) .
Pathway: